Man with curly black hair and beard wears a striped shirt under his white lab coat, safety googles, and blue latex gloves while examining a test tube of transparent green liquid.

Inside Seres

Seres is defined by its extraordinary people, and their passion is what drives us on our mission to help patients.

Make your mark on the medical breakthroughs of tomorrow

At Seres, we’re leading the microbiome revolution — and our most revolutionary asset is our team. We’re courageous and deeply collaborative, and above all we’re passionate about the commitment we’ve made to blaze a new trail for the benefit of patients.

We are proud of our achievements thus far — including moving multiple novel therapeutics to the clinic for patients — achievements made possible by our amazing teams across the company.

Just as combinations of bacteria perform challenging biological tasks together, integration of our diverse expertise and insights is allowing us to drive the microbiome revolution and change the face of medicine for patients in need.

Join the revolution. Explore our open jobs below.

Meet our
team

One of the most exciting projects I’ve been involved in is putting together our state-of-the-art gnotobiotic program. This technology is really unique to Seres, and I was very proud to have been part of it. Outside of work I enjoy travel, riding motorcycles, and I am an avid bar trivia connoisseur.

Keith H.

Manager, In Vivo Pharmacology

A highlight of working at Seres is the ability to collaborate with scientists of many different backgrounds, which has given me the opportunity to learn new skill sets and think of problems from different angles. When I'm not at Seres I sing co-lead for a six-part rock band with friends from the North Shore. We currently play mostly covers, and we plan to book some shows at local venues while we work on more of our original material.

Shelby E.

Senior Associate in Analytical Development

It was great to be part of the team involved with our cluster computing project. The project took a lot of hard work but has become the backbone of our computational pipeline at Seres. One day I would like to create an AI/deep learning framework that can accelerate drug design by continuously crunching data and generating hypotheses without human intervention. I'd obviously make sure it didn't become sentient and evil... more Wall-E, less HAL.

Varun M.

Senior Scientist, Computational Biology

I always look forward to R&D's Data and Donuts presentations, which is a casual environment to present research-in-progress and receive feedback and ideas from a wider audience. Outside of science, I have taught group exercise for almost ten years. It started as a fun way to get physical activity and exert energy in college, but now is a great way to end the workday and maintain a healthy life-work balance.

Mahmoud S.

Scientist II, Microbiology and Functional Screening

I love to interact with the people at Seres, from old coworkers up to new hires – that is the best part of my day. My passion outside of work is drawing, painting and custom action figures. I want to put together several paintings for an exhibition someday.

Luis M.

Facilities Manager

Get to
know us

There’s so much more of Seres to discover. Find our team on LinkedIn and connect with us to start a conversation.

See who you know at Seres

Open
positions

Seres Therapeutics is a dynamic biotechnology company in Cambridge MA pioneering innovative Ecobiotic® microbiome therapeutics. Seres has promising late clinical stage programs for treatment of recurrent Clostridium difficile infection and Ulcerative Colitis and is well-positioned to become the first company to commercialize a new therapeutic modality comprising ecologies of commensal bacteria. Seres plans to enter the clinic with multiple new product candidates in a range of therapeutic areas including immuno-oncology and inflammation to build upon its field-leading portfolio of intellectual property and know-how.

Quality Control Analyst:

We are looking for a proactive team player and rapid learner to help us analyze these exciting microbial therapies. Seres has developed a suite of proprietary QC analytical techniques spanning microbiology, molecular biology, and chemistry that we routinely use to release and characterize our products. As part of the role, you will have the opportunity to learn these novel methods and execute them to help us move our products forward to patients. Additionally, we are a highly collaborative team, and your work will support critical efforts from functions across the company, including Analytical Development/ASAT, Manufacturing/MSAT, Facilities and Engineering, and Quality Assurance. If you have a strong positive attitude and are excited about learning and applying new skills while also potentially making a difference in people’s lives, this may be the role for you.

 

Responsibilities:

  • Execute proprietary and compendial assays routinely on in-process, characterization and release samples to generate accurate, precise, trustworthy data to support clinical drug product release and stability studies
  • Analyze and record data rigorously and critically, and rapidly report out results and flag any assay issues or out-of-specification (OOS) results observed
  • Promote QC process improvements by authoring and updating assay SOPs and test methods as needed
  • Qualify and maintain analytical instruments for use and troubleshoot issues as necessary
  • Work with more senior staff to develop, qualify, and troubleshoot analytical methods for process monitoring and product release

Qualifications:

  • BS degree in microbiology, molecular biology, biochemistry or a related discipline and 1-2 years of laboratory experience, preferably in assay execution
  • Team player capable of working in a fast-paced environment; Highly proactive and interested in rapidly learning new skills and helping the team
  • Strong analytical, communication, documentation, and organizational skills
  • Experience executing microbiological assays (i.e. CFU, microscopy, microbiological identification), molecular assays (qPCR, etc.) and/or biochemical assays is valuable
  • Ability to operate analytical instrumentation (i.e. microscopy, titration equipment, microplate readers etc.)
  • Working knowledge of MS Office Suite and office productivity software and the ability to quickly learn new software; Experience with the use of Electronic Laboratory Notebooks/LIMS is a plus
  • Previous experience with cGMP operations and regulations is a plus
Apply for the Analyst, Quality Control position

Associate Director, Donor Analytical Sciences

Seres Therapeutics is well-positioned to become the first company to bring an approved microbiome drug to patients through our proprietary discovery and design platform.  We identify key alterations in the microbiome that are associated with specific diseases and are designing live bacterial ecologies to act as therapeutics.

The Associate Director, Donor Analytical Sciences will work closely with our Analytical Development and Quality Control teams in the development of microbial and molecular assays to enable safe biologic material procurement and characterization of our donor population.  This is a highly visible and business critical position; the impact you will have on Seres as a key contributor is tremendous. 

What’s in it for you?

You will learn about the exciting science of the microbiome and its impact on human health and disease.  You will gain an understanding of the biology of specific microbes and the composition of the microbiome in healthy and diseased individuals that allows us to identify “keystone” organisms and functional pathways whose absence or over-abundance may be driving a particular form of dysbiosis.  This is an opportunity to have a significant impact on the development of a novel class of therapeutics for various disease areas.  You will learn that our Ecobiotic® drugs are compositions of commensal microbes that are designed to catalyze the transition to a healthy ecology of the microbiome and treat serious human conditions including inflammatory, metabolic, and infectious diseases.  This is a unique opportunity to build out new capabilities and programs to support a critical function for Seres.  In a nutshell, come to Seres and put your many years of experiences to great use while learning something different that is beyond exciting.

How do you know if you are the right fit?

If you are an experienced professional with a strong background in microbiology, molecular microbiology, assay development and validation, project management and cross functional management, you will find this leadership opportunity incredibly engaging.    

As Associate Director you will partner with internal and external, cross-functional teams to begin building a Donor Sciences department in support of a unique biologic material procurement program.  This candidate will manage critical, commercial and research laboratory processes and be a compliance subject matter expert in a growing organization.

This is an incredible opportunity for someone who will get excited about leading the charge on a unique program in support of a pioneering new class of therapeutics.  You are someone who challenges himself/herself on meeting operational milestones with seamless execution and within established budgets.  You know what it takes to successfully manage operational teams and sites and have demonstrated full competence in continual process improvement and documentation development.

Apply for the Associate Director, Donor Analytical Sciences position

As part of the Quality Systems Shared Services Group, this role will act as a QS champion working with GxP functions (GCP, GMP) supporting operational activities responsible for Quality Supplier Management, Quality Risk Management, Internal Auditing and Inspection Readiness.  This role will also support activities (not limited to) including internal audits and assessments, GMP inspection readiness, Quality Risk Management and general compliance initiatives.  

 

What You’ll Do:

  • Generates and implements policies and procedures in support of Seres Quality Management
  • Harmonize procedures and processes that ensure compliance with regulations and industry standards.
  • Lead and support GMP readiness activities for new facilities, laboratories and/or support areas.
  • Ensures compliance to internal policies and applicable regulatory requirements
  • Manage and supports inspection readiness efforts for all GxP operations.
  • Coordinate and assist the development of inspection and internal audit responses. 
  • Support supplier qualification activities for all GxP vendors
  • Assist operational areas with development, review and approval support for FMEA, root cause analysis, investigations and other GxP records as required.
  • Provides QA review and approval of CAPA Plans, vendor/supplier approvals and other continuous product and process improvement support.
  • Provides compliance oversight for efficiency improvements based on functional area, site and quality continuous improvement projects.
  • Prepare and review key performance metrics supporting Risk Management, supplier qualification and CAPA programs are conducted per policies and SOPs
  • Perform trending of KPIs to assist QA partners and organization in identifying potential risks and supporting continuous improvement
  • Pro-actively evaluate quality system programs and processes for continuous improvement opportunities.
  • Support Seres GxP Quality System projects, programs and functional area initiatives as required

What You’ll Bring:

  • Bachelor’s degree in life sciences, or engineering with minimum 10 years of experience in the pharmaceutical or biotechnology industry
  • Minimum 2 years of experience in the management of quality systems and compliance.
  • Working knowledge of drug development process and supporting GMP operations
  • Advanced knowledge and demonstrated experience in the applicable GXP regulations, FDA Good Manufacturing and Clinical Practices, ICH Guidelines, Global Drug Development Regulations and Guidance’s and Computer System Validation.
  • Strong verbal and written communication (including presentation) and customer management skills.
  • Ability to work independently or as a team member/leader
  • ASQ Certified Quality Auditor (CQA), ASQ Certified Manager of Quality/Organizational Excellence, or SQA Registered Quality Assurance Professional preferred.
Apply for the Associate Director, Quality Assurance position

Associate Director, Supply Chain (Warehouse, Inventory, Logistics)

Seres Therapeutics is well-positioned to become the first company to bring an approved microbiome drug to patients through our proprietary discovery and design platform.  We identify key alterations in the microbiome that are associated with specific diseases and are designing live bacterial ecologies to act as therapeutics.

The Associate Director is a key position in the Supply Chain and greater CMCQS organizations influencing and collaborating cross-functionally with internal and external partners and will:

  • Manage warehouse, inventory, logistics and personnel in a continuous state of compliance with IATA, DOT, FDA, GMP, SOX and OSHA standards
  • Assess, analyze and optimize warehouse capacity including ambient and temperature-controlled storage locations
  • Implement and maintain inventory programs such as visual reorder point (KANBAN) and Vendor Managed Inventory (VMI) programs for uninterrupted supply of materials
  • Maintain data integrity and accuracy through execution of inventory transactions – receipt through issuance, cycle count and physical inventory
  • Ensure timely material receipt, put-away, picking, issue, and shipments – domestic and international
  • Develop and oversee execution against all SOPs related to receipt, inspection, storage, and delivery of GMP materials
  • Oversee the hiring, training, development, and performance management of Warehouse as well as the establishment of key performance indicators and service level agreements for Warehouse Operations
  • Ensure compliance with ERP and quality systems/processes
  • Maintain GMP warehouse space, coordinating with Facilities for equipment ordering, installation, calibration and maintenance

 

What’s in it for you?

This opportunity is ideal for anyone who possesses excellent verbal and written communication skills and who will drive excellence and collaboration while ensuring adherence to SOX, Trade, IATA, DOT, OSHA and FDA compliance.  The ideal candidate will possess a solid understanding of domestic and international shipping of cold chain products in the Biotech/Lifesciences industry and associated documentation needs; and have a strong working knowledge of and experience with ERP systems (Oracle, SAP, etc.); and GMP warehouse operations.

 

How do you know if you’re the right fit?

This is an incredible opportunity for someone who has proven experience with progressive responsibility in supply chain, warehouse and logistics management and inventory control.  You are excited about leading continuous improvement initiatives within the GMP Warehouse and provide input to broader materials management improvement initiatives.  You are someone who challenges themself with achieving key performance targets for inventory accuracy, timeliness of transactions and closure of quality systems.  You know what it takes to be successful in managing a compliant warehouse and have a vision of and experience with implementing sustainable and robust processes and procedures.  If you are flexible and driven, aren’t afraid of rolling up your sleeves to pitch in, and have managed a GMP Warehouse, implemented raw material programs and processes, achieved a high level of inventory accuracy, you will find this opportunity incredibly engaging. 

Apply for the Associate Director, Supply Chain position

Job Summary

Seres Therapeutics is seeking a Associate II, CMC Manufacturing to join our team who will be responsible for supporting manufacturing operations and clinical supplies across several phases of clinical trials. This individual will be involved in the execution and documentation of cGMP manufacturing processes, and operations pertaining to drug substance and drug product manufacturing. S/he will also ensure proper safety and aseptic protocols for floor operations. This individual will collaborate with multiple support groups such as Quality Control, Quality Assurance, Bioprocess and Facilities to support the transfer of process changes to manufacturing operations.

Job Responsibilities

  • Prepare raw materials, media culture, solutions and consumables according to Standard Operating Procedures and safety regulations for manufacturing operations
  • Author Standard Operating Procedures, batch records, Corrective and Preventative Actions and deviations
  • Ensure availability of required materials and equipment for manufacturing operations
  • Follow and complete daily standard operation procedures by completing reports, performing batch records, logging equipment, maintaining safety procedures and reviewing manufacturing documentation to ensure compliance
  • Maintain cleanliness and orderliness of manufacturing facilities
  • Provide training to and review safety procedures with junior employees
  • Plan production activities within assigned area
  • Perform as Subject Matter Expert or system owner for specific pieces of equipment

Required Skills and Qualifications

  • Bachelor's degree in Science, Engineering or a related field with 5-8 years of experience in biopharma clinical manufacturing or relevant industry
  • Previous experience in a cGMP or clinically regulated environment
  • Strong organizational skills and attention to detail
  • Excellent communication skills and strong team player
  • Flexible and adaptable work schedule

 

Apply for the Associate II, Manufacturing position

Job Summary

Seres Therapeutics is seeking an Associate, CMC Manufacturing to join our team who will be responsible for supporting manufacturing operations and clinical supplies across several phases of clinical trials. This individual will be involved in the execution and documentation of cGMP manufacturing processes, and operations pertaining to drug substance and drug product manufacturing. S/he will also ensure proper safety and aseptic protocols for floor operations. This individual will collaborate with multiple support groups such as Quality Control, Quality Assurance, Bioprocess and Facilities to support the transfer of process changes to manufacturing operations.

Job Responsibilities

  • Operation of bioprocess equipment for microbial cultures, recovery and purification
  • Execution of Batch Records and Author Standard Operating Procedures
  • Troubleshooting of manufacturing and process challenges
  • Management of raw materials and consumables required for manufacturing
  • Proactive identification and mitigation of risks
  • Identification of process changes and improvements
  • Initiation and support of deviation/quality event investigations and close-out

Required Skills and Qualifications

  • Bachelor’s degree in Life Sciences or Biotechnology Certificate with 0-1 years ‘experience in Biotech manufacturing
  • Experienced with aseptic techniques
  • Exposure to cGMP standards for clinical and/or commercial manufacturing
  • Knowledge of biotech manufacturing process and equipment in some aspects of fermentation, filtration, purification, and formulation processes
  • Flexible with schedule and willingness to work long shifts if necessary
  • Ability to work in a fast-paced and constantly changing environment to meet current challenges
  • Works well independently and in group settings

 

Apply for the Associate, Manufacturing position

Bioinformatics Programmer, Bioinformatics & Scientific Computing

Who are we?

Seres Therapeutics is well-positioned to become the first company to bring an approved microbiome drug to patients through our proprietary discovery and design platform. We identify key alterations in the microbiome that are associated with specific diseases and are designing live bacterial ecologies to act as therapeutics. Our research and discovery efforts are elucidating the mechanisms that microbes employ to modulate host immunity and inflammation. The power of the Seres platform has demonstrated therapeutic potential in infectious and inflammatory disease, immune regulation, and immuno-oncology. Seres is conducting multiple clinical trials, including a Phase 3 study of SER-109 to treat multiply recurrent C. difficile infection, a Phase 2b study of SER-287 in ulcerative colitis, and a Phase 1b study in collaboration with the Parker Institute of Cancer Immuno-Therapy to evaluate how treatment with SER-401 can improve response to anti-PD-1 therapy in metastatic melanoma. Our clinical programs provide industry-leading data, driving our preclinical efforts to elucidate how commensal microbes modulate the human immune and metabolic state and guiding our preclinical pipeline of the next generation of microbial therapeutics.

What is in it for you?

The Bioinformatics Programmer in the Bioinformatics & Scientific Computing group will have the opportunity to aid in the design, development, and maintenance of automated frameworks for data delivery, data download, and workflow integration.  You will work within an engineering team to understand user requirements and implement software solutions.  As part of Research and Development, your work will affect every part of drug design, from basic microbiome research to clinical data analysis.  You will be part of a great team that emphasizes collaboration and learning new skills.

Your initial responsibilities will include:

  • Understanding complex microbiome datasets used for ingestion into Elastic or other database systems

  • Developing tools and workflows for transforming NGS and other ‘Omics datasets into actionable outputs

  • Writing software that is reusable, testable, efficient, well architected, and well commented

  • Collaborating with team members to deliver production-ready, rigorously tested software

  • Understanding business needs from team members across R&D functional areas

We seek candidates with these qualifications:

  • Enthusiasm for learning with a team-driven mindset in a diverse, dynamic, and fast-paced environment
  • BS degree or higher in Computer Science, Bioinformatics or a related technical discipline
  • 3+ years of experience in research-and-development setting in bioinformatics
  • Proficiency in Python, Linux shell scripting, and version control tools (git, Subversion)
  • Experience with NGS and other ‘Omics datasets
  • Experience in shared High-Performance Computing (HPC) environments (S/UGE, LSF)
  • Experience with Nextflow workflow framework, R, and scientific data visualization desired
  • Experience with cloud compute infrastructure (AWS, GCP, and/or Azure)
  • Experience with database technologies (SQL, PostgreSQL, Oracle) and Elastic a plus
  • Familiarity with IaaS DevOps tool (Ansible, Terraform)
  • Software containerization experience a plus
  • Knowledge of OOP principles a plus
  • Familiarity with regulatory qualification/validation documentation and testing
  •  
Apply for the Bioinformatics Programmer, Bioinformatics & Scientific Computing position

Seres Therapeutics is well-positioned to become the first company to bring an approved microbiome drug to patients through our proprietary discovery and design platform. We identify key alterations in the microbiome that are associated with specific diseases and are designing live bacterial ecologies to act as therapeutics.

The Service Desk Engineer / Lab Support is a key position in the IT and greater QC organizations, collaborating cross-functionally with internal and external partners and will:

  • Take lead role on the support of all lab computers.
  • Experience with qualification and validation of computer systems following GxP protocols as required.
  • Collaborating with the functional groups and vendors when software updates are required familiarity with IT change management.
  • Experience in documenting systems Inventory and maintenance history and following GxP protocols as required.
  • Works with outside vendor to update security patches and determine compatibly of version of software.
  • Manage Help Desk tickets in a timely manner.
  • Respond to customer issues via Jira, email, Zoom and Teams.
  • Run diagnostics to resolve customer reported issues.
  • Familiar with Windows 10 and XP, macOS, Active Directory and O365.

What’s in it for you?

  • This opportunity is ideal for anyone who possesses experience with Laboratory Information systems and is comfortable working with Scientists and with the IT Team in a highly regulated environment. The successful candidate will operate with a high degree of autonomy in the Lab space.

 

How do you know if you’re the right fit?

  • If you are an experienced professional with a two to three years of background in Life Sciences with help desk lab support experience, you will find this opportunity incredibly engaging.
  • This is an incredible opportunity for someone who will get excited about leading the charge on a unique program in support of a pioneering new class of therapeutics.

 

Physical Requirements:

The candidate will work in a laboratory environment, required to lift to 25 lbs., may be required to stand for long periods of time while performing duties.

Apply for the Contract Opportunity – Service Desk Engineer position

Seres is seeking a Director of Regulatory Operations to lead the submission activities for multiple products across their diverse portfolio.  The chosen candidate will have the opportunity to break new ground and be part of filing and potentially winning approval for the first microbiome therapeutic in the United States.

Director, Regulatory Operations will lead the regulatory operations function as well as cross-functional teams in the successful delivery of Regulatory submissions for all development programs and projects.  This person will be accountable for ensuring health authority submissions are compiled accurately, in their entirety, within specified timelines while maintaining quality. This person will be responsible for leading the collaboration with Seres staff, as well as external vendors, regarding health authority submission logistics (content, deliverable timing, status, issue resolution, review and QC).  This includes recording and tracking content and eCTD lifecycle of all applications, ensuring proper archiving of each submission, and providing eCTD/submission guidance and training to Seres staff.

Essential Responsibilities:

  • Leads the submission planning efforts for all development programs.
  • Works closely with Regulatory Affairs to effectively identify, plan for and manage timely completion of development programs regulatory milestones.
  • Sets priorities on upcoming submissions to health authorities and maintains status of assigned submissions.  Prepares and manages the Health Authority Application Tracker as appropriate.
  • Manages regulatory budgets to support all phases of drug development projects.
  • Closely interacts with team members and authoring community to define submission logistics, scheduling and priorities.
  • Set and manage expectations, highlighting and resolving issues, ensuring regular communications and managing internal and external activities.
  •  
  • Supports Development Teams in understanding the document requirements for Health Authority submissions
  • Manage Management System for all regulated documents to ensure proper lifecycle management, to track and monitor development programs regulatory objectives/goals, archival and storage of regulatory submissions.
  • Manage and track the internal review of larger Health Authority applications to ensure accuracy/completeness prior to submission. This includes maintaining constant communication with internal team and eCTD vendor to ensure timely issue identification, resolution and implementation.
  • Acts as primary liaison with publishing vendor(s) for all eCTD submissions.  Oversees the compilation and collaboration with the eCTD vendors for all major and routine submissions (including but not limited to NDAs, IND, MAAs, amendments, supplements, promotional material (OPDP/APLB).
  • Provides guidance and feedback to colleagues in terms of eCTD standards for electronic submissions (e.g., templates, style guides, hyperlinking, bookmarking, technology, Regulations, EDMS).
  • Aids in the proper management, retention, and version control of all applicable submission documentation.
  • Prepares and maintains SOPs, work instructions and checklists related to templates, electronic document management, electronic submission processes, submission document QC, and archiving.
  • Manages and develops a competent and technically skilled submission operations organization (both FTE’s and Contract).

Experience and Qualifications:

  • Bachelor’s degree or equivalent is required
  • 10 years of directly related experience, preferably in Regulatory Operations.
  • Experience with an electronic document management system and/or workflows.
  • Prior interaction with eCTD vendors and experience with outsourcing.
  • Experience and knowledge in the preparation of global regulatory submissions (e.g., original IND/IND amendments, CTAs, NDA/BLA/MAA).
  • Knowledge of eCTD content/format requirements and working knowledge of ICH and FDA guidance relevant to electronic regulatory submissions
  • Proficient with Microsoft Office products and Adobe Acrobat.
  • Experience and knowledge of eCTD and publishing tools (e.g., metadata, STF, ISIToolbox).
  • Experience working in a team environment.
  • Ability to manage people and projects.
  • Ability to work both independently with direction and within project teams.
  • Excellent verbal and written communication skills are essential.
  • Proactive, strong organizational skills, the ability to prioritize workload and pay close attention to detail.
  • Demonstrates personal initiative, responsibility, flexibility, the ability to work under limited supervision, and be able to handle multiple project assignments.
  • Strong interpersonal skills and the ability to deal effectively with a variety of personnel including medical, scientific, and manufacturing staff.

 

Critical Skills:

    • Strategic problem-solving skills.
    • Excellent organizational and multitasking abilities.
    • A team player with leadership skills.
    • Superior communication skills.
    • Scientific curiosity strongly preferred

 

Apply for the Director, Regulatory Operations position

Seres Therapeutics is a dynamic biotechnology company in Cambridge MA pioneering innovative Ecobiotic® microbiome therapeutics.  Seres has promising late clinical stage programs and is well-positioned to become the first company to commercialize a new therapeutic modality comprising ecologies of commensal bacteria.  Seres plans to enter the clinic with multiple new product candidates in a range of therapeutic areas including infectious disease, inflammation and metabolic disease and to build upon its field-leading portfolio of intellectual property and know-how.

 

Job Summary

Seres Therapeutics is seeking a highly motivated Senior Engineer to join our Manufacturing Sciences & Technology team. We are focused on developing and supporting manufacturing processes to enable cGMP manufacturing of Seres Therapeutics’ pipeline products. In the role you will work closely with various groups, including Bioprocess Development, Manufacturing Operations, Facilities & Engineering, Supply Chain, Regulatory, Quality Control, and Quality Assurance.

 

Job Responsibilities

  • Responsible for new product scale-up, process optimization, technology transfer and process validation activities.
  • Serve as technical expert for the drug substance and drug product manufacturing processes.
  • Manage timelines and deliverables from project ideation through completion.
  • Facilitate criticality and risk assessments for manufacturing processes and raw materials, soliciting and incorporating feedback from the appropriate SMEs.
  • Author and execute experiments for process development, characterization, & scale up following the principles of Quality by Design (QbD).
  • Provide technical support for GMP manufacturing runs, supporting manufacturing through quality systems; deviations, CAPAs, & change controls.
  • Perform process performance analysis and trend process performance.

Required Skills and Qualifications

  • BS or MS degree in Biomedical Engineering, Chemical Engineering, Mechanical Engineering or related technical discipline.
  • BS with 5+ years of experience or MS with 4+ years of experience in manufacturing sciences, process development, process validation, or related field.
  • Prior experience with tech transfer, risk assessments, and quality systems in GMP environment.
  • Prior experience with some or all of the following: single-use systems, tangential flow filtration, fermentation, lyophilization.
  • Familiar with FDA and EU regulations and GMP standards.
  • To be successful, you will possess sound understanding of engineering fundamentals, be independently motivated, able to work under aggressive timelines to achieve meaningful objectives, comfortable in a dynamic environment, detail oriented, and possess creative problem-solving abilities. 
  • We are looking for a person who meshes well with our culture – eager to dig into whatever work is needed, with a quick learning curve, and do so with high quality results. Collaboration and communication with laboratory and manufacturing colleagues is key!

 

Apply for the Engineer II, MSAT position

Head of US Commercial

The Head of US Commercial is responsible for leading development and execution of commercial strategy for the entire portfolio of products from Seres Therapeutics, the leading microbiome company.

 

One of the first commercial hires for the company, this individual’s primary focus will be on preparing for the successful US launch of our SER-109 oral capsule in recurrent C. difficile infection while ensuring pipeline strategies and development plans are optimized to support successful commercialization. 

 

Reporting directly to the Chief Commercial and Strategy Officer, this key leader will have the opportunity to design and build a world class organization to support commercialization for all Seres products.  Remit includes but may not be limited to:  providing leadership and direction of all marketing and commercial strategies; ensuring strong strategic plans are developed and executed to support appropriate adoption of Seres’ novel therapeutics; developing cross-functional launch plans; partner with program teams in assessment of data generation and label expansion plans in support of enhancing commercial value; identification of innovative go-to-market models; determination of optimal size and structure of commercial organization including sales force and commercial operations team (e.g. business insights and analytics). 

 

As a member of the commercial leadership team, this position will work across the organization to ensure external stakeholder perspectives are reflected in key deliverables and decisions supporting commercial launch plans and clinical development.  

 

Seres Therapeutics, Inc., (Nasdaq: MCRB) is a leading microbiome therapeutics platform company developing a novel class of multifunctional bacterial consortia that are designed to functionally interact with host cells and tissues to treat disease. Seres’ SER-109 program achieved the first-ever positive pivotal clinical results for a targeted microbiome drug candidate and has obtained Breakthrough Therapy and Orphan Drug designations from the FDA. The SER-109 program is being advanced for the treatment of recurrent C. difficile infection and has potential to become a first-in-class FDA-approved microbiome therapeutic. Seres’ SER-287 program has obtained Fast Track and Orphan Drug designations from the FDA and is being evaluated in a Phase 2b study in patients with active mild-to-moderate ulcerative colitis. Seres is developing SER-401 in a Phase 1b study in patients with metastatic melanoma, SER-301 for ulcerative colitis and SER-155 to prevent mortality due to gastrointestinal infections, bacteremia and graft versus host disease.

Seres Therapeutics is a member of the Flagship Pioneering family of companies, affording this individual broad exposure and access to other industry leaders in the Flagship fold. 

 

Seres is based in Cambridge, MA.  We recognize the complexities introduced by COVID-19 on travel, necessity for office-based work, and increased value of remote working.  This position will require a mix of Seres corporate office and external stakeholder interfaces therefore we are affording the right candidate flexibility with respect to their East Coast location.  Post-COVID travel will be required to support these critical interfaces. 

 

Responsibilities:

    • Lead commercial teams in developing go to market strategy and launch plans (positioning, messaging, distribution, pricing, launch sequence, etc.)
    • Design and build optimal sales and marketing organization to support the launch of SER-109 
    • As different teams are onboarded, ensure activities and resource planning of the Market Access, Market Research, Patient Advocacy, Sales, Marketing, and Medical Affairs groups are in alignment with commercial strategy
    • Build strong relationships with KOLs, patient advocacy groups, and key customers to establish mutually beneficial partnerships that advance standard of patient care and understanding of the role of microbiome therapeutics in key diseases of interest
    • Create revenue and unit forecasts for pipeline products to provide an assessment of asset value to product development teams and to support the portfolio planning initiatives including production forecasts
  • Ensure development of market and opportunity assessments and target product profiles to establish roadmap for pipeline product development; ensure optimized LCM plans are developed to maximize value of each Seres asset
  • Infuse commercial perspective to internal portfolio strategic reviews, making well-supported recommendations to maximize portfolio value  
  • Point of liaison for current and potential future external partners (e.g. with ex-North American partner Nestle Health Sciences for SER-109 and SER-287) to integrate commercial strategy, where appropriate for partnered assets
  • Attract, develop, and retain staff members; Inspire and elevate capabilities of others

 

  • Provide prompt and objective feedback and coaching to enhance or improve performance by setting expectations and holding individuals accountable for performance and behavior
  • Ensure compliance with corporate policies and procedures, as well as US healthcare laws and regulations

 

 

Qualifications:

  • Minimum of a bachelor’s degree; advanced degree preferred
  • 15+ years of broad and progressive experience within commercial roles ideally spanning marketing, new product planning, access, and sales
  • Recent experience running US P&Ls and recent US product launch experience
  • Demonstrated leadership ability and track record; building high-performing commercial teams; strong talent assessment capability and the ability to attract, retain and effectively coach top industry talent to superior performance. Strong ability to effectively engage and motivate people and lead change
  • Superb strategist / visionary who can originate competitive and creative strategies.  Independent thinker with analytical savvy. Ability to quickly manipulate numbers, draw conclusions and exhibit solid problem solving. High level of financial business acumen
  • Prior experience with strategic alliances (establishing and managing strategic relationships such as joint ventures, co-marketing agreements and development partnerships) a plus
  • This hire will be in a role of significant visibility within and outside the company and will possess superb communications skills, the comportment of a professional and the skill of a diplomat.  Strong customer orientation
  • Resourceful, flexible, adaptable, diplomatic, and able to effectively deal with ambiguity
  • Possesses a good blend of strategic and operational experience with the ability to see the big picture and strong attention to detail
  • Fit with Seres culture and values, especially encouraging candidates with diverse backgrounds and those who are inclined to listen as much as they are to decide/lead.    Seres is a highly collaborative environment and, therefore, consensus building will be a critical skill to ensure success in this role
     
Apply for the Head of US Commercial position

Your Mission?

As part of the Quality Systems Shared Services Group, this role will act as a QS compliance lead working with GxP functions (GCP, GMP) supporting operational activities including but not limited to Supplier Management, Quality Risk Management, CSV projects and auditing activities.  This role will also support cross-functional GxP compliance initiatives.  

 

What You'll Do:

  • Evaluate GxP procedures and processes to ensure compliance with regulations, industry standards and internal controls.
  • Support GMP readiness activities for new facilities, laboratories and/or support areas.
  • Ensures compliance to internal policies and applicable regulatory requirements
  • Manage and supports inspection readiness efforts for all GxP operations.
  • Assist with qualification and 
  • Assist QA Partners and department leads in performing investigations, deviations, CAPAs, change controls and other GMP quality project initiatives
  • Support the supplier qualification review process as required for all GxP vendors identified 
  • Support CSV projects via review and approval of associated lifecycle documents. 
  • Review of QC laboratory qualification reports and associated records in support of validation 
  • Assist operational areas with development, review and approval support for FMEA, root cause analysis, investigations and other GxP records as required.
  • Provides QA review and approval of CAPA Plans and other continuous product and process improvement support as identified
  • Identify opportunities for efficiency improvements based on functional area, site and quality continuous improvement projects.
  • Assist with preparing and reviewing key performance metrics supporting quality management 
  • Support Seres GxP Quality System projects, programs and functional area initiatives as required
Apply for the Principal Associate, Quality Systems position

Job Summary

Seres Therapeutics is seeking a Principle Associate, CMC Manufacturing to join our team who will be responsible for supporting manufacturing operations and clinical supplies across several phases of clinical trials. This individual will be involved in the execution and documentation of cGMP manufacturing processes, and operations pertaining to drug substance and drug product manufacturing. S/he will also ensure proper safety and aseptic protocols for floor operations. This individual will collaborate with multiple support groups such as Quality Control, Quality Assurance, Bioprocess and Facilities to support the transfer of process changes to manufacturing operations.

Job Responsibilities

  • Prepare raw materials, media culture, solutions and consumables according to Standard Operating Procedures and safety regulations for manufacturing operations
  • Leading and or performing on floor activates
  • Author Standard Operating Procedures, Batch Records, Corrective and Preventative Actions and Deviations
  • Trouble shoot process issues and communicating to supporting teams
  • Participate in investigations and quality events
  • Ensure availability of required materials and equipment for manufacturing operations
  • Follow and complete daily standard operation procedures by completing reports, performing batch records, logging equipment, maintaining safety procedures and reviewing manufacturing documentation to ensure compliance
  • Maintain cleanliness and orderliness of manufacturing facilities
  • Ensure Manufacturing Suite is inspection ready at all times
  • Provide training to and review safety procedures with junior employees
  • Plan production activities within assigned area
  • Adjust activities and resources as needed
  • Perform as Subject Matter Expert or system owner for specific pieces of equipment
  • Model Manufacturing Core Behaviors
  • Collaborate with affected group or individuals to resolve or mitigate effects of an error or abnormality
  • Thoroughly understand the process critical path
  • Provide Manufacturing daily updates
  • Understand how to spread the knowledge/experience and utilize talent of the team members to maintain SME’s across process steps

Required Skills and Qualifications

  • Bachelor's degree in Science, Engineering or a related field with 5-8 years of experience in biopharma clinical manufacturing or relevant industry
  • Previous experience in a cGMP or clinically regulated environment
  • Strong organizational skills and attention to detail
  • Excellent communication skills and strong team player
  • Flexible and adaptable work schedule

 

Apply for the Principle Associate, Manufacturing position

Scientist, Analytical Development 

Seres Therapeutics is well-positioned to become the first company to bring an approved microbiome drug to patients through our proprietary discovery and design platform.  We identify key alterations in the microbiome that are associated with specific diseases and are designing live bacterial ecologies to act as therapeutics in areas as diverse as infectious and inflammatory disease, immune regulation, and immuno-oncology.

The Scientist, Analytical Development will work closely with our Analytical Development, Quality Control, and Research & Development teams in the development of microbial and molecular assays to ensure safe and effective bacterial therapeutics for the patients who need them.  This is a fantastic opportunity for a creative scientist who can apply their expertise to the unique challenges faced when characterizing and releasing therapeutics comprised of communities of bacteria. 

 

What’s in it for you?

This is an opportunity to have a significant impact on the development of a novel class of therapeutics for various disease areas while learning about the exciting science of the microbiome and its impact on human health and disease.  

 

How do you know if you’re the right fit?

This is an incredible opportunity for someone who will get excited about developing assays that are robust and capable of supporting key decisions to move our programs forward.  If you are flexible and driven, have worked in a fast-paced organization, and enjoy the challenge of forging a path forward in a new field, you would find this novel opportunity very engaging.  

In order to develop the sorts of assays Seres needs, you should be a PhD-level scientist, or equivalent, with significant assay development experience in the area of molecular biology and/or microbiology.   You should have an excellent attitude with an infectious excitement around learning and teaching your craft.   Experience with assay qualification or validation is a plus. Other desirable skills include sequencing, qPCR/dPCR, probe-based hybridization assays, LC-MS, IC, and automated liquid handlers.

Apply for the Scientist, Analytical Development position

Seres is seeking a Senior Director, Commercial Regulatory  to lead the advertising, promotional, and labelling activities for multiple products across their diverse portfolio.  The chosen candidate will have the opportunity to break new ground and be part of filing and potential launch for the first microbiome therapeutic in the United States.

The person will be responsible for providing strategic guidance on the development and implementation of a creative and compliant labeling, advertising and promotion program for pre-launch and commercial microbiome portfolio. She/he will work with limited supervision to review and provide strategic advice on advertising & promotion materials, in accordance with the requirements of the US Food and Drug Administration (FDA), company policy, and business goals and objectives. He/she will also ensure effective communication and constructive working relationships with regulatory authorities and internal/external collaborators.

 

Responsibilities

  • Serves as the primary regulatory advertising and promotion reviewer on cross-functional Promotional Review Boards (PRB) for the successful launch of the company’s commercial programs, and on Medical Review Boards (MRB) for the compliant scientific exchange of information of investigational programs.
  • Acts as primary contact with FDA’s Office of Prescription Drug Promotion (OPDP), including responding to agency inquiries and managing company requests for advisory review.
  • Develops solutions to complex US promotional issues by utilizing scientific and regulatory knowledge to support business objectives and initiatives while effectively managing business risks.
  • Identifies and provides guidance on development and improvement of policies, processes, and standards for promotional materials and related activities.
  • Works closely with Regulatory counterparts to ensure that global development strategies result in commercially viable labeling, in support of desired promotional claims.
  • Participates in training of personnel on advertising and promotional materials, as required.
  • Provides oversight to relevant external vendors and consultants, particularly as it relates to ex-US advertising and promotional activities.
  • Monitors and keeps organization up-to-date on US regulatory promotional environment (e.g., the issuance of new FDA regulations/guidance, relevant FDA enforcement action and general awareness of industry practices, including those of competitors).
  •  

    Qualifications

  • BA/BS Degree required.
  • Advanced degree preferred (MS, PhD, PharmD, or JD).
  • Significant years of pharmaceutical industry experience, with experience focused on the regulatory review of advertising and promotion materials for prescription drug products.
  • Experience with launching new products and/or new indications a must
  • Direct experience interacting with OPDP required.
  • Experience working on an accelerated approval product a plus.
  • Strong interpersonal and oral and written communication skills.
  • Able to innovate, analyze, and solve problems with minimal supervisory input, anticipating and identifying regulatory risks and making recommendations to management, as appropriate.
  • Solid understanding of business goals and common marketing concepts/tools, including the internet and social media.
  • Experience in managing multiple global programs a plus
Apply for the Senior Director, Commercial Regulatory Strategy position

Seres is seeking a Regulatory Strategy Leader for multiple products across their diverse portfolio.  The chosen candidate will have the opportunity to break new ground and be part of filing and potentially winning approval for the first microbiome therapeutic in the United States as well as other markets.   

The Sr Director Regulatory Strategy will have a key role contributing to build a successful clinical regulatory strategy function at Seres and will lead key interactions between Seres and the FDA. The role includes participation in defining and implementing the strategy from first-in-human trial until marketing authorization and subsequent adjustments. 

The Sr Director Regulatory Strategy will be responsible for ensuring alignment on regulatory strategy, activities, and timelines between project, product, and program teams. A successful Senior Director of Regulatory Affairs will build effective partnerships with counterparts across the R&D organization, as well as external partners. 

Responsibilities:

The areas of responsibilities will include

  • Participate in the redefinition of the regulatory strategy for the company.
  • Provide regulatory support in preparation of documents such as Investigator Brochure, clinical study protocols, and Informed Consent.
  • Provide regulatory advice to all stakeholders in support of the development of clinical study reports.
  • Plan and supervise preparation and filing of regulatory submissions for assigned products/programs from IND to NDA/BLA as well as Fast Track, Breakthrough, RMAT, and ODD to US agencies and institutions.
  • Plan, supervise, and represent Seres at regulatory agency meetings.
  • Interpret and explain regulatory agency communications to stakeholders across Seres’  program/project teams to ensure accurate functional area responses to agency requests and comments.
  • Represent Seres on co-development teams and liaison with co-development partners on regulatory planning and strategy.
  • Participate in building the Regulatory Affairs team.
  • Stay current on changing regulatory environment, advise Seres on new and changing regulations that may impact ongoing development programs, and work with QA to implement new or changed operating procedures for ongoing programs.
  •  

    Requirements:

  • Industry Experience:
    • Significant experience in regulatory affairs within the biotech or pharmaceutical industry, including direct experience interacting with the FDA; experience with CBER preferred. Experience with foreign regulatory agencies a plus.
    • Experience with US regulatory submissions, Orphan Drug Designation, Rolling BLA, Fast Track and Breakthrough therapy designations in the US  as well as foreign agency equivalents considered a plus.
    • Experience planning and managing complex regulatory submissions.
    • Regulatory or scientific experience across a variety of disease areas considered a plus.
    • Experience collaboratively developing Target Product Profiles is required.
    • Experience developing and implementing a Clinical Development Plan is required.
    • Experience working with external medical/scientific experts to support development planning and strategy.
  • Critical Skills:
    • Strategic problem-solving skills.
    • Excellent organizational and multitasking abilities.
    • A team player with leadership skills.
    • Superior communication skills.
    • Scientific curiosity strongly preferred
Apply for the Senior Director, Regulatory Strategy position

Senior Manager, Donation Collection Facility (DCF)

Seres Therapeutics is well-positioned to become the first company to bring an approved microbiome drug to patients through our proprietary discovery and design platform.  We identify key alterations in the microbiome that are associated with specific diseases and are designing live bacterial ecologies to act as therapeutics.

The Senior Manager, Donation Collection Facility will work closely with the manufacturing, scientific and quality assurance teams to drive biologic material procurement in support of C. difficile patients.  This is a business-critical position; the impact you have on Seres as a key contributor is tremendous.  This is a fantastic opportunity for a very experienced professional with strong experiences in operational management and oversight of a novel biologics procurement program.    

What’s in it for you?

You’ll learn all about our microbiome research and gain an understanding of the biology of specific microbes and the composition of the microbiome in healthy and diseased individuals that allows us to identify “keystone” organisms and functional pathways whose absence or over-abundance may be driving a particular form of dysbiosis.  Learn that our Ecobiotic® drugs are compositions of commensal microbes that are designed to catalyze the transition to a healthy ecology of the microbiome and treat serious human conditions including inflammatory, metabolic, and infectious diseases.  In a nutshell, come to Seres and put your many years of experiences to great use while learning something different that is beyond exciting.

How do you know if you’re the right fit?

This is an incredible opportunity for someone who will get excited about leading the charge on a unique program in support of a pioneering new therapeutic.  You are someone who challenges himself/herself on meeting operational milestones with seamless execution and within established budgets and quality assurance parameters.  You know what it takes to be successful managing operational sites and teams and have demonstrated full competence in continual process improvement and documentation development.

If you have worked in an organization where you managed the procurement of donor derived products, plasma, or blood products, or have experience in facility design and management, you would find this novel leadership opportunity incredibly engaging.

Apply for the Senior Manager, Donation Collection Facility (DCF) position

Senior Manager, Donor Operations – Recruitment Management

What’s in it for you?

Seres Therapeutics is well-positioned to become the first company to bring an approved microbiome drug to patients through our proprietary discovery and design platform.  We identify key alterations in the microbiome that are associated with specific diseases and are designing live bacterial ecologies to act as therapeutics.

The Donor Operations, Recruitment Manager will work closely with our operational teams and facilities to recruit healthy volunteers in support of our donor derived products.  This is a highly visible and business critical position; the impact you have on Seres as a key contributor is tremendous.  This is a fantastic opportunity for a very experienced professional with strong experience in strategic management and execution of a sophisticated, custom-built advertising campaign for volunteer recruitment and screening.    

 

What’s in it for you?

This opportunity is ideal for anyone who excels at creative problem solving and who will drive towards challenging recruitment targets.  Our approach to making drugs is rigorous and refined, and so is our search for donor-volunteers.  This is not your everyday recruitment campaign or effort; our volunteers are unique and our strategic approach to finding them reflects that.  If you are driven, creative and a cross functional team player, you need to consider this position.  It’s truly a one-in-a-million opportunity.

You’ll learn all about our microbiome research and gain an understanding of the biology of specific microbes and the composition of the microbiome in healthy and diseased individuals that allows us to identify “keystone” organisms and functional pathways whose absence or over-abundance may be driving a particular form of dysbiosis. Learn that our Ecobiotic® drugs are compositions of commensal microbes that are designed to catalyze the transition to a healthy ecology of the microbiome and treat serious human conditions including inflammatory, metabolic, and infectious diseases. In a nutshell, come to Seres and put your many years of experiences to great use while learning something different that is beyond exciting.

 

How do you know if you’re the right fit?

This is an incredible opportunity for someone who will get excited about leading the charge on a unique program in support of a pioneering new therapeutic. You are someone who challenges himself/herself on meeting recruitment milestones with seamless execution and within established budgets. You know what it takes to be successful in managing a high-volume program with attention to detail at a rapid pace.

If you are flexible and driven, have worked in a fast-paced organization, and have managed a strategic volunteer recruitment campaign and telephone screening program, you would find this novel opportunity incredibly engaging. 

Apply for the Senior Manager, Donor Operations - Recruitment Management position

Senior Medical Director, Clinical Development

Reporting to the CMO, this  Senior Medical Director will serve as the Medical Lead for Graft vs Host disorder trials. Working closely with the CMO, the Senior Medical Director will set the clinical development strategy and will work with cross-functional multidisciplinary study teams on clinical trial design and execution.

Key Responsibilities
 

  • Prepare and execute the clinical development plans, in conjunction with other relevant functional areas,
  • Serve as medical monitor for the assigned trials, assessing issues related to protocol conduct and subject safety.
  • Participate in the development of study protocols, statistical analysis plans, investigator's brochures, and other key study documents in conjunction with other line functions and with minimal guidance
  • Serve on cross-functional study teams for assigned trials, working with other team members to achieve efficient, high-quality study execution, and data analysis
  • Participate in the preparation of regulatory documents in support of regulatory submissions, including clinical section of INDs and CTAs, safety reports, responses to regulatory authorities, clinical study reports, and other documents as appropriate
  • Interface with regulatory authorities as appropriate
  • Act as liaison between clinical development and other internal groups at Seres for assigned studies
  • Provide medical and development leadership for cross-functional teams, including for external innovation/business development
  • Represent the company to outside medical personal in the development of clinical protocols and study conduct
  • Represent the company to outside stakeholders
     

Education/Experience
 

  • MD, or DO
  • Minimum of 5 years Pharmaceutical/Biotech industry experience, including time managing clinical trials and clinical development programs
  • Board certification/eligibility, another relevant specialty area, is highly desired
  • Clinical development and/or clinical experience in rare disease
  • Ability to work collaboratively in a fast-paced, team-based matrix environment

     
Apply for the Senior Medical Director, Clinical Development position

Seres Therapeutics is a dynamic biotechnology company in Cambridge MA pioneering innovative Ecobiotic® microbiome therapeutics. Seres has promising late clinical stage programs and is well-positioned to become the first company to commercialize a new therapeutic modality comprising ecologies of commensal bacteria. Seres plans to enter the clinic with multiple new product candidates in a range of therapeutic areas including infectious disease, inflammation and metabolic disease and to build upon its field-leading portfolio of intellectual property and know-how.


Job Summary
Seres Therapeutics is seeking a highly motivated Senior MSAT (Manufacturing, Science, and Technology)  Engineer to join our Manufacturing Sciences & Technology team. We are focused on developing and supporting manufacturing processes to enable cGMP manufacturing of Seres Therapeutics’ pipeline products. In the role you will work closely with various groups, including Bioprocess Development, Manufacturing Operations, Facilities & Engineering, Supply Chain, Regulatory, Quality Control, and Quality Assurance.


Job Responsibilities

  • Responsible for new product scale-up, process optimization, technology transfer and process validation activities.
  • Serve as technical expert for the drug substance and drug product manufacturing processes on internal and external teams.
  • Manage timelines, deliverables, and personnel from project ideation through completion.
  • Lead and facilitate criticality and risk assessments for manufacturing processes and raw materials, soliciting and incorporating feedback from the appropriate SMEs.
  • Author and execute experiments for process development, characterization, & scale up following the principles of Quality by Design (QbD).
  • Provide technical support for GMP manufacturing runs, supporting manufacturing through quality systems; deviations, CAPAs, & change controls.
  • Perform process performance analysis and trend process performance.

Required Skills and Qualifications

  • BS or MS degree in Biomedical Engineering, Chemical Engineering, Mechanical Engineering or related technical discipline.
  • BS with 8+ years of experience or MS with 6+ years of experience in manufacturing sciences, process development, process validation, or related field.
  • Prior experience with tech transfer, risk assessments, and quality systems in GMP environment.
  • Prior experience with some or all of the following: single-use systems, tangential flow filtration, fermentation, lyophilization.
  • Familiar with FDA and EU regulations and GMP standards.
  • To be successful, you will possess sound understanding of engineering fundamentals, be independently motivated, able to work under aggressive timelines to achieve meaningful objectives, comfortable in a dynamic environment, detail oriented, and possess creative problem-solving abilities.
  • We are looking for a person who meshes well with our culture – eager to dig into whatever work is needed, with a quick learning curve, and do so with high quality results. Collaboration and communication with laboratory and manufacturing colleagues is key!
Apply for the Senior MSAT Engineer position

Seres Therapeutics is well-positioned to become the first company to bring an approved?microbiome drug to patients through our proprietary discovery and design platform. We identify?key alterations in the microbiome that are associated with specific diseases and are designing live bacterial ecologies to act as therapeutics.?

The Quality Assurance Specialist I will be critical in supporting the growing needs of Seres Manufacturing and Analytical Functions. Reporting into the Manager of Quality Assurance, this role will provide quality oversight for Manufacturing and Quality Operations, including documentation review of executed quality records.

This position is a great opportunity for an experienced professional with strong verbal and written communication skills, customer management skills, and Quality experience in the pharmaceutical or biotechnology industry. Experience working in cross-functional teams, working collaboratively with CMO’s (Contract Manufacturing Organizations), building and managing relationships with key stakeholders are skills that will support excelling in this role.   

 

Apply for the Specialist I, Quality Assurance position

System Engineer, Bioinformatics & Scientific Computing

Who are we?

Seres Therapeutics is well-positioned to become the first company to bring an approved microbiome drug to patients through our proprietary discovery and design platform. We identify key alterations in the microbiome that are associated with specific diseases and are designing live bacterial ecologies to act as therapeutics. Our research and discovery efforts are elucidating the mechanisms that microbes employ to modulate host immunity and inflammation. The power of the Seres platform has demonstrated therapeutic potential in infectious and inflammatory disease, immune regulation, and immuno-oncology. Seres is conducting multiple clinical trials, including a Phase 3 study of SER-109 to treat multiply recurrent C. difficile infection, a Phase 2b study of SER-287 in ulcerative colitis, and a Phase 1b study in collaboration with the Parker Institute of Cancer Immuno-Therapy to evaluate how treatment with SER-401 can improve response to anti-PD-1 therapy in metastatic melanoma. Our clinical programs provide industry-leading data, driving our preclinical efforts to elucidate how commensal microbes modulate the human immune and metabolic state and guiding our preclinical pipeline of the next generation of microbial therapeutics.

 

What is in it for you?

The System Engineer in the Bioinformatics & Scientific Computing group will have the opportunity to aid in the maintenance and improvement of shared R&D compute infrastructure.  You will work closely with a Senior Engineer to monitor, develop, deploy, and update physical and virtualized servers using DevOps tools.  As part of Research and Development, your work will affect every part of drug design, from basic microbiome research to clinical data analysis.  You will be part of a great team that emphasizes collaboration and learning new skills.

 

Your initial responsibilities will include:

  • Performing backup, file replication, and script management for servers
  • Planning, coordinating, and managing installation and maintenance activities of complex systems
  • Collaborating with DevOps colleagues to improve processes or resolve complex technical problems
  • Working with R&D colleagues directly to troubleshoot platform or connectivity issues
  • Analyzing networks and data centers, recommending improvements and technology upgrades
  • Enhance infrastructure and reconfigure software/hardware
  • Configuration, installation, and deployment of new infrastructure
  • Performing operational support tasks as required to maintain infrastructure uptime
  • Owning problem resolution, facilitating discussions, and providing status updates

 

We seek candidates with these qualifications:

  • Technical aptitude with an attention to details and a curious mind
  • BS degree in CS, Engineering, or a related technical discipline
  • Must be able to lift (up to 50 lbs.) and install server equipment using provided tools.
  • 3+ years of experience supporting end-user systems including datacenter operations
  • Strong background in Linux Administration and data center operations with a working knowledge of scripting: Unix shell, Perl, Python, and/or Ansible
  • Good knowledge of storage platforms and file systems (XFS, ZFS, Spectrum Scale)
  • Good understanding of network protocols, experience with InfiniBand a plus
  • Experience with monitoring and logging tools
  • Experience with the Atlassian toolkit
  • AWS and/or containerization experience a plus
Apply for the System Engineer, Bioinformatics & Scientific Computing position

Our latest
news

Recurrent C. diff study now enrolling
An open-label study of SER-109

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Seres announces positive topline results for SER-109
SER-109 met primary endpoint in Phase 3 study in C. difficile

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