Man with curly black hair and beard wears a striped shirt under his white lab coat, safety googles, and blue latex gloves while examining a test tube of transparent green liquid.

Inside Seres

Seres is defined by its extraordinary people, and their passion is what drives us on our mission to help patients.

Make your mark on the medical breakthroughs of tomorrow

At Seres, we’re leading the microbiome revolution — and our most revolutionary asset is our team. We’re courageous and deeply collaborative, and above all we’re passionate about the commitment we’ve made to blaze a new trail for the benefit of patients.

We are proud of our achievements thus far — including moving multiple novel therapeutics to the clinic for patients — achievements made possible by our amazing teams across the company.

Just as combinations of bacteria perform challenging biological tasks together, integration of our diverse expertise and insights is allowing us to drive the microbiome revolution and change the face of medicine for patients in need.

Join the revolution. Explore our open jobs below.

Meet our
team

One of the most exciting projects I’ve been involved in is putting together our state-of-the-art gnotobiotic program. This technology is really unique to Seres, and I was very proud to have been part of it. Outside of work I enjoy travel, riding motorcycles, and I am an avid bar trivia connoisseur.

Keith H.

Manager, In Vivo Pharmacology

A highlight of working at Seres is the ability to collaborate with scientists of many different backgrounds, which has given me the opportunity to learn new skill sets and think of problems from different angles. When I'm not at Seres I sing co-lead for a six-part rock band with friends from the North Shore. We currently play mostly covers, and we plan to book some shows at local venues while we work on more of our original material.

Shelby E.

Senior Associate in Analytical Development

It was great to be part of the team involved with our cluster computing project. The project took a lot of hard work but has become the backbone of our computational pipeline at Seres. One day I would like to create an AI/deep learning framework that can accelerate drug design by continuously crunching data and generating hypotheses without human intervention. I'd obviously make sure it didn't become sentient and evil... more Wall-E, less HAL.

Varun M.

Senior Scientist, Computational Biology

I always look forward to R&D's Data and Donuts presentations, which is a casual environment to present research-in-progress and receive feedback and ideas from a wider audience. Outside of science, I have taught group exercise for almost ten years. It started as a fun way to get physical activity and exert energy in college, but now is a great way to end the workday and maintain a healthy life-work balance.

Mahmoud S.

Scientist II, Microbiology and Functional Screening

I love to interact with the people at Seres, from old coworkers up to new hires – that is the best part of my day. My passion outside of work is drawing, painting and custom action figures. I want to put together several paintings for an exhibition someday.

Luis M.

Facilities Manager

Get to
know us

There’s so much more of Seres to discover. Find our team on LinkedIn and connect with us to start a conversation.

See who you know at Seres

Open
positions

Associate Director, Donor Analytical Sciences

Seres Therapeutics is well-positioned to become the first company to bring an approved microbiome drug to patients through our proprietary discovery and design platform.  We identify key alterations in the microbiome that are associated with specific diseases and are designing live bacterial ecologies to act as therapeutics.

The Associate Director, Donor Analytical Sciences will work closely with our Analytical Development and Quality Control teams in the development of microbial and molecular assays to enable safe biologic material procurement and characterization of our donor population.  This is a highly visible and business critical position; the impact you will have on Seres as a key contributor is tremendous. 

What’s in it for you?

You will learn about the exciting science of the microbiome and its impact on human health and disease.  You will gain an understanding of the biology of specific microbes and the composition of the microbiome in healthy and diseased individuals that allows us to identify “keystone” organisms and functional pathways whose absence or over-abundance may be driving a particular form of dysbiosis.  This is an opportunity to have a significant impact on the development of a novel class of therapeutics for various disease areas.  You will learn that our Ecobiotic® drugs are compositions of commensal microbes that are designed to catalyze the transition to a healthy ecology of the microbiome and treat serious human conditions including inflammatory, metabolic, and infectious diseases.  This is a unique opportunity to build out new capabilities and programs to support a critical function for Seres.  In a nutshell, come to Seres and put your many years of experiences to great use while learning something different that is beyond exciting.

How do you know if you are the right fit?

If you are an experienced professional with a strong background in microbiology, molecular microbiology, assay development and validation, project management and cross functional management, you will find this leadership opportunity incredibly engaging.    

As Associate Director you will partner with internal and external, cross-functional teams to begin building a Donor Sciences department in support of a unique biologic material procurement program.  This candidate will manage critical, commercial and research laboratory processes and be a compliance subject matter expert in a growing organization.

This is an incredible opportunity for someone who will get excited about leading the charge on a unique program in support of a pioneering new class of therapeutics.  You are someone who challenges himself/herself on meeting operational milestones with seamless execution and within established budgets.  You know what it takes to successfully manage operational teams and sites and have demonstrated full competence in continual process improvement and documentation development.

Apply for the Associate Director, Donor Analytical Sciences position

As part of the Quality Systems Shared Services Group, this role will oversee the Seres GxP Audit /Inspection program and management of external auditors.  This includes internal, external, vendor, CRO and other assessments/audits as determined to support the business performed on behalf of Seres Therapeutics. 

What You’ll Do:

  • Develops and implements an anual GxP audit plan in coordination with functional areas including but not limited to Manufacturing, Donation Operations, R&D and Clinical.
  • Select and oversee external auditors.
  • Perform co-audits/audits as needed or requested.
  • Maintain training records, CVs, SOPs, etc. of external auditors
  • Schedule audits with external auditors per audit plan.
  • Oversee the development of audit plans and work with the business leads to assure they meet the needs within CMC, R&D and Clinical.
  • Review audit reports to assure they are clear and cover the most important information to support successful development of CAPA’s
  • Prepare audit performance metrics to assure audit program is conducted per standards and SOPs
  • Perform audit trending of audit findings to assist QA and organization in identifying potential risks and supporting continuous improvement
  • Assure all audit plans, reports, CAPAs and certificates are appropriately archived
  • Support supplier qualification activities including review of questionnaires and vendor approvals. 
  • Evaluate Audit and Inspection Program processes for continuous improvement opportunities.
  • Support Seres GxP Quality System projects, programs and functional area initiatives as required

 

What You’ll Bring:

  • Bachelor’s degree in life sciences, or engineering with minimum 10 years of experience in the pharmaceutical or biotechnology industry
  • Minimum 5 years of GxP QA Audit and/or Regulatory Inspection experience.
  • Advanced knowledge and demonstrated experience in the applicable GXP regulations, FDA Good Manufacturing and Clinical Practices, ICH Guidelines, Global Drug Development Regulations and Guidance’s and Computer System Validation.
  • Advanced experience in the conduct and reporting of audits and the translation of findings into corrective actions plans that mitigate risks to the company, to subject protection and data integrity.
  • Demonstrated ability to effectively organize and execute tasks.
  • Strong verbal and written communication (including presentation) and customer management skills.
  • ASQ Certified Quality Auditor (CQA), ASQ Certified Manager of Quality/Organizational Excellence, or SQA Registered Quality Assurance Professional preferred.
Apply for the Associate Director, GxP Audits and Inspections position

Associate Director, Supply Chain (Warehouse, Inventory, Logistics)

Seres Therapeutics is well-positioned to become the first company to bring an approved microbiome drug to patients through our proprietary discovery and design platform.  We identify key alterations in the microbiome that are associated with specific diseases and are designing live bacterial ecologies to act as therapeutics.

The Associate Director is a key position in the Supply Chain and greater CMCQS organizations influencing and collaborating cross-functionally with internal and external partners and will:

  • Manage warehouse, inventory, logistics and personnel in a continuous state of compliance with IATA, DOT, FDA, GMP, SOX and OSHA standards
  • Assess, analyze and optimize warehouse capacity including ambient and temperature-controlled storage locations
  • Implement and maintain inventory programs such as visual reorder point (KANBAN) and Vendor Managed Inventory (VMI) programs for uninterrupted supply of materials
  • Maintain data integrity and accuracy through execution of inventory transactions – receipt through issuance, cycle count and physical inventory
  • Ensure timely material receipt, put-away, picking, issue, and shipments – domestic and international
  • Develop and oversee execution against all SOPs related to receipt, inspection, storage, and delivery of GMP materials
  • Oversee the hiring, training, development, and performance management of Warehouse as well as the establishment of key performance indicators and service level agreements for Warehouse Operations
  • Ensure compliance with ERP and quality systems/processes
  • Maintain GMP warehouse space, coordinating with Facilities for equipment ordering, installation, calibration and maintenance

 

What’s in it for you?

This opportunity is ideal for anyone who possesses excellent verbal and written communication skills and who will drive excellence and collaboration while ensuring adherence to SOX, Trade, IATA, DOT, OSHA and FDA compliance.  The ideal candidate will possess a solid understanding of domestic and international shipping of cold chain products in the Biotech/Lifesciences industry and associated documentation needs; and have a strong working knowledge of and experience with ERP systems (Oracle, SAP, etc.); and GMP warehouse operations.

 

How do you know if you’re the right fit?

This is an incredible opportunity for someone who has proven experience with progressive responsibility in supply chain, warehouse and logistics management and inventory control.  You are excited about leading continuous improvement initiatives within the GMP Warehouse and provide input to broader materials management improvement initiatives.  You are someone who challenges themself with achieving key performance targets for inventory accuracy, timeliness of transactions and closure of quality systems.  You know what it takes to be successful in managing a compliant warehouse and have a vision of and experience with implementing sustainable and robust processes and procedures.  If you are flexible and driven, aren’t afraid of rolling up your sleeves to pitch in, and have managed a GMP Warehouse, implemented raw material programs and processes, achieved a high level of inventory accuracy, you will find this opportunity incredibly engaging. 

Apply for the Associate Director, Supply Chain position


 

Clinical Supply Manager

 

Seres Therapeutics is well-positioned to become the first company to bring an approved microbiome drug to patients through our proprietary discovery and design platform.  We identify key alterations in the microbiome that are associated with specific diseases and are designing live bacterial ecologies to act as therapeutics. Come join our effort!

 

What’s in it for you?

Aside from demonstrating your prowess in clinical supply management, you’ll get to work cross-functionally with CMC, QA, Clinical Teams, and external vendors to forecast clinical supply needs and implement strategy for timely supply and oversight of trial materials. You will be generating, maintaining, and owning supply plans to enable proactive forecasting of trial needs to drive both internal and external production activities for supply of trials at all phases. You will oversee packaging, labeling, and distribution vendors. You will implement the strategy to ensure availability and distribution of finished goods for studies across Seres’ full portfolio. Implementing, testing, and overseeing Interactive Response Technology (IRT) systems to ensure seamless supply of trial materials is just one of the ways you will be able to demonstrate your attention to detail, organizational, and collaborative skills in this role. You will coach and mentor junior staff and support new-hire trainings. You’ll also make your mark by helping to shape and develop the Clinical Supply processes at Seres as we continue to grow.   

 

How do you know if you’re the right fit?

First, you will be a person who can demonstrate your project management chops as well as your creative approach to problem solving. While this role requires a solid background of Clinical Supply experience, ranging from packaging to clinical distribution, we are also looking for demonstrated ability to work both independently and as part of cross-functional teams that span the Clinical Operations, CMC, Regulatory, Quality, R&D, and Finance groups. You’ll be excited to show off your strong organizational and technical skills, including your ability to manage competing priorities in a fast-paced work environment. The right fit will exhibit excellent written and communication skills with a strong proficiency in Microsoft Excel.

 

The other stuff

This is typically a role best suited for an experienced (5+ years) clinical supply manager, but someone from a related field with clinical supply chain experience and a BS in Supply Chain, Life Sciences, Engineering, or related discipline shouldn’t hesitate to apply. Successful candidates will have experience starting up clinical trials and the IRT/IxRS systems customized to help run them. Candidates should have working knowledge of GMP/GCP processes as well as experience with international labeling, shipping, and import/export of clinical supplies. Strong understanding of clinical trial management requirements from primary packaging to finished goods distribution to study sites is desirable.

 

 

Apply for the Clinical Supply Manager position

Why Seres Therapeutics

At Seres Therapeutics, we have a singular mission to transform the lives of patients by targeting the underlying cause of their diseases. We are pioneers and explorers, charting a new course. You’ll have the opportunity to truly define your area of focus.

If you have a pioneering spirit, join us as we ignite a revolution in the treatment of disease through the microbiome.

What’s Your Mission?

Seres needs a Clinical Trial Manager (CTM), who will report in to the Senior Director of Clinical Operations. The mission of this role is to drive the execution of a new clinical program. As such, the role directly impacts Seres’ ultimate goal of developing novel microbiome therapies to patients in need.

This CTM will need to independently organize and manage multiple clinical trial activities including facilitating cross-functional team meetings, managing vendors, and addressing protocol related questions. S/he would also be ensuring that study milestones are met and that the trial is completed in accordance with the protocol, study milestones and within budget.

What You’ll Do.

  • Responsible for all operational management of clinical trials. Position serves as lead for a new clinical program
  • Selection and management of CRO, vendors and consultants that are involved with the clinical trial
  • Oversee vendor(s) to ensure compliance with contract specifications (including budget), SOPs and the study Oversight Plan, including review of CRO progress reports and metrics
  • Coordinate financial and legal documentation exchange between sponsor, vendors and sites
  • Establish/maintain study milestones and ensure accurate tracking and reporting of study metrics and timelines
  • Organize and facilitate/document study cross-functional team meetings
  • Serve as point person for trial execution internally & externally
  • Coordinate and participate in data reviews in conjunction with Data Management staff
  • Review study Trial Master File periodically for quality control measures
  • Review and provide input for clinical study documents such as informed consent, protocols, Investigator’s Brochure, recruitment materials, yearly updates to the regulatory authorities and status updates
  • Review and approve study related plans generated by CRO and study vendors
  • Responsible for oversight of identification and selection of investigator sites
  • Responsible for communication and escalation of study related risks and issues as required
  • Ensure study staff is appropriately trained on relevant guidelines, regulations and SOPs
  • Assist in the oversight of monitoring activities and site visits
  • May represent Clinical Operations in cross-functional initiatives
  • Participate in review and revision of departmental SOPs, provide support to establish and maintain operational infrastructure
  • Manage and attend Investigator Meetings, conferences, and perform co-monitoring as needed.

What You’ll Bring.

  • Knowledge – thorough understanding of GCP/regulatory requirements
  • Proactiveness – the ability to identify challenges and risks and implement appropriate actions with some supervision
  • Motivation – highly motivated and self-starter; able to organize and perform complex tasks with minimal supervision
  • Strong communication – able to communicate clearly (in writing and verbally)
  • Collaboration – to coordinate activities of internal cross-functional study team as well as external vendors as applicable
  • Leadership – skills to lead and motivate a team for timely study execution
  • Open-mindedness – listen to ideas from others and seek guidance when applicable; inform manager as situations arise to brainstorm and seek best solutions

You May Also Bring.

  • Demonstrated computer skills including functional knowledge of Microsoft packages and ability to develop proficiency in technical systems and programs
  • Experience developing, reviewing, and approving study operational plans including site monitoring and risk mitigation strategies, trial budgets, site feasibility and clinical metrics tracking reports
  • Experience managing CROs, vendors, and/or clinical trial consultants
  • Preferred Education & Experience.
  • B.S. (or equivalent experience) and 3 - 6 years of relevant work experience
  • M.S. (or equivalent experience) and 2 - 4 years of relevant work experience

Who We Are.

Seres Therapeutics is a clinical stage biotherapeutic company focused on discovering and developing Ecobiotic™ therapeutic products, novel drugs to treat important diseases by targeting the underlying biology of the human microbiome. Founded by Flagship Pioneering, Seres is pioneering the first therapeutics that catalyze a shift to health by augmenting the biology of the microbiome. Current candidates span infectious, metabolic, and inflammatory diseases. For more information, please visit http://serestherapeutics.com/

Apply for the Clinical Trial Manager position

Head of US Commercial

The Head of US Commercial is responsible for leading development and execution of commercial strategy for the entire portfolio of products from Seres Therapeutics, the leading microbiome company.

 

One of the first commercial hires for the company, this individual’s primary focus will be on preparing for the successful US launch of our SER-109 oral capsule in recurrent C. difficile infection while ensuring pipeline strategies and development plans are optimized to support successful commercialization. 

 

Reporting directly to the Chief Commercial and Strategy Officer, this key leader will have the opportunity to design and build a world class organization to support commercialization for all Seres products.  Remit includes but may not be limited to:  providing leadership and direction of all marketing and commercial strategies; ensuring strong strategic plans are developed and executed to support appropriate adoption of Seres’ novel therapeutics; developing cross-functional launch plans; partner with program teams in assessment of data generation and label expansion plans in support of enhancing commercial value; identification of innovative go-to-market models; determination of optimal size and structure of commercial organization including sales force and commercial operations team (e.g. business insights and analytics). 

 

As a member of the commercial leadership team, this position will work across the organization to ensure external stakeholder perspectives are reflected in key deliverables and decisions supporting commercial launch plans and clinical development.  

 

Seres Therapeutics, Inc., (Nasdaq: MCRB) is a leading microbiome therapeutics platform company developing a novel class of multifunctional bacterial consortia that are designed to functionally interact with host cells and tissues to treat disease. Seres’ SER-109 program achieved the first-ever positive pivotal clinical results for a targeted microbiome drug candidate and has obtained Breakthrough Therapy and Orphan Drug designations from the FDA. The SER-109 program is being advanced for the treatment of recurrent C. difficile infection and has potential to become a first-in-class FDA-approved microbiome therapeutic. Seres’ SER-287 program has obtained Fast Track and Orphan Drug designations from the FDA and is being evaluated in a Phase 2b study in patients with active mild-to-moderate ulcerative colitis. Seres is developing SER-401 in a Phase 1b study in patients with metastatic melanoma, SER-301 for ulcerative colitis and SER-155 to prevent mortality due to gastrointestinal infections, bacteremia and graft versus host disease.

Seres Therapeutics is a member of the Flagship Pioneering family of companies, affording this individual broad exposure and access to other industry leaders in the Flagship fold. 

 

Seres is based in Cambridge, MA.  We recognize the complexities introduced by COVID-19 on travel, necessity for office-based work, and increased value of remote working.  This position will require a mix of Seres corporate office and external stakeholder interfaces therefore we are affording the right candidate flexibility with respect to their East Coast location.  Post-COVID travel will be required to support these critical interfaces. 

 

Responsibilities:

    • Lead commercial teams in developing go to market strategy and launch plans (positioning, messaging, distribution, pricing, launch sequence, etc.)
    • Design and build optimal sales and marketing organization to support the launch of SER-109 
    • As different teams are onboarded, ensure activities and resource planning of the Market Access, Market Research, Patient Advocacy, Sales, Marketing, and Medical Affairs groups are in alignment with commercial strategy
    • Build strong relationships with KOLs, patient advocacy groups, and key customers to establish mutually beneficial partnerships that advance standard of patient care and understanding of the role of microbiome therapeutics in key diseases of interest
    • Create revenue and unit forecasts for pipeline products to provide an assessment of asset value to product development teams and to support the portfolio planning initiatives including production forecasts
  • Ensure development of market and opportunity assessments and target product profiles to establish roadmap for pipeline product development; ensure optimized LCM plans are developed to maximize value of each Seres asset
  • Infuse commercial perspective to internal portfolio strategic reviews, making well-supported recommendations to maximize portfolio value  
  • Point of liaison for current and potential future external partners (e.g. with ex-North American partner Nestle Health Sciences for SER-109 and SER-287) to integrate commercial strategy, where appropriate for partnered assets
  • Attract, develop, and retain staff members; Inspire and elevate capabilities of others

 

  • Provide prompt and objective feedback and coaching to enhance or improve performance by setting expectations and holding individuals accountable for performance and behavior
  • Ensure compliance with corporate policies and procedures, as well as US healthcare laws and regulations

 

 

Qualifications:

  • Minimum of a bachelor’s degree; advanced degree preferred
  • 15+ years of broad and progressive experience within commercial roles ideally spanning marketing, new product planning, access, and sales
  • Recent experience running US P&Ls and recent US product launch experience
  • Demonstrated leadership ability and track record; building high-performing commercial teams; strong talent assessment capability and the ability to attract, retain and effectively coach top industry talent to superior performance. Strong ability to effectively engage and motivate people and lead change
  • Superb strategist / visionary who can originate competitive and creative strategies.  Independent thinker with analytical savvy. Ability to quickly manipulate numbers, draw conclusions and exhibit solid problem solving. High level of financial business acumen
  • Prior experience with strategic alliances (establishing and managing strategic relationships such as joint ventures, co-marketing agreements and development partnerships) a plus
  • This hire will be in a role of significant visibility within and outside the company and will possess superb communications skills, the comportment of a professional and the skill of a diplomat.  Strong customer orientation
  • Resourceful, flexible, adaptable, diplomatic, and able to effectively deal with ambiguity
  • Possesses a good blend of strategic and operational experience with the ability to see the big picture and strong attention to detail
  • Fit with Seres culture and values, especially encouraging candidates with diverse backgrounds and those who are inclined to listen as much as they are to decide/lead.    Seres is a highly collaborative environment and, therefore, consensus building will be a critical skill to ensure success in this role
     
Apply for the Head of US Commercial position

HR Operations

Seres Therapeutics is well-positioned to become the first company to bring an approved microbiome drug to patients through our proprietary discovery and design platform.  We identify key alterations in the microbiome that are associated with specific diseases and are designing live bacterial ecologies to act as therapeutics.

The Human Resources Operations professional will work closely with colleagues throughout Seres.  This is a highly visible position and perfect for you if you thrive on being involved in all parts of the HR function.  If your strength is in HR systems but you want to increase your knowledge in other areas of HR, then this is the ideal opportunity for you.  We want to increase the HR exposure of a highly motivated HR individual who considers themself as having an incredible aptitude for learning.  The impact you have on Seres as a key contributor is tremendous.

 

What’s in it for you?

We are a small team of HR professionals who are very eager to help increase your HR knowledge.  You’ll have the opportunity to get heavily involved in areas of HR that you thought might not be possible or might have been years away.  And, you’ll be doing it at a company who is leading the industry in a new kind of science - the microbiome.   In a nutshell, come to Seres and put your HR experiences and personal curiosity to great use while learning something different that is beyond exciting.

 

How do you know if you’re the right fit? 

This is an incredible opportunity for someone who gets excited about creating efficient processes that directly drives the organization to reach goals and milestone; who has a reputation for flawless execution of HR systems & data management; and, most importantly, who is natural at partnering with colleagues to field questions and troubleshoot issues.  Your success will be driven by your ownership attitude, pride in your work, your ability to take initiative, and knowing that no task as too large or too small.

If you are a creative problem solver and a cross functional team player, you need to consider this position.

Apply for the Manager, HR Operations position

Research Associate, Molecular Technologies

Who are we?

Seres Therapeutics is well-positioned to become the first company to bring an approved?microbiome drug to patients through our proprietary discovery and design platform.  We identify?key alterations in the microbiome that are associated with specific diseases and are designing live bacterial ecologies to act as therapeutics. Our research and discovery efforts are elucidating the mechanisms that microbes employ to modulate host immunity and inflammation. The power of the Seres platform has demonstrated therapeutic potential in infectious and inflammatory disease,  immune regulation, and immuno-oncology.  Seres is conducting multiple clinical trials, including a Phase 3 study of SER-109 to treat multiply recurrent C. difficile infection, a Phase 2b study of SER-287 in ulcerative colitis, and a Phase 1b study in collaboration with the Parker Institute of Cancer Immuno-Therapy to evaluate how treatment with SER-401 can improve response to anti-PD-1 therapy in metastatic melanoma.  Our clinical programs provide industry-leading data, driving our preclinical efforts to elucidate how commensal microbes modulate the human immune and metabolic state and guiding our preclinical pipeline of the next generation of microbial therapeutics. 

 

What is in it for you?

The Research Associate, Molecular Technologies will have the opportunity to participate in the development and execution of molecular and genomics methods to support the discovery and development of microbiome therapeutics. By rigorously examining details of these molecular workflows, you will understand, define, and improve our molecular toolset to assay microbes and microbial communities.

 

Your initial responsibilities will include:

  • Develop, document, improve, and execute molecular methods to characterize microbiological samples such as automated and manual nucleic acid extractions, qPCR, sequencing, or probe-based hybridization assays

  • Organize and maintain laboratory space, prepare reagents, and manage sample inventory.

  • Maintain detailed records of and effectively communicate procedures and results

  • Participate in team discussions including presenting results of and contextualizing your work

  • Organize and track samples, data, and independently or collaboratively analyze and summarize results

  • Communicate effectively with researchers and management from R&D, CMC, and clinical groups 

  • Effectively prioritize project activities, as shifting needs are common in our fast-paced company

 

We seek candidates with these qualifications:

  • 2 +  years of experience performing molecular techniques including nucleic acid extraction, PCR/qPCR, sequencing, FISH, or similar assays, preferably in a biotech or pharma setting

  • Experience with laboratory automation such as liquid handlers preferred

  • Demonstrated strong organizational and interpersonal skills, effective communication skills, rigorous quantitative approach, and keen attention to detail

  • Enthusiasm for a team-driven mindset in a diverse and dynamic environment

  • BS or MS degree in biology, biochemistry, microbiology or a related field

Apply for the Research Associate, Molecular Technologies position

Associate II or Senior Associate, Donation Operations Quality Assurance

What’s in it for you?

Seres Therapeutics is well-positioned to become the first company to bring an approved microbiome drug to patients. We identify?key alterations in the microbiome that are associated with specific diseases and are designing live bacterial ecologies to act as therapeutics.?

The Associate II/Senior Associate, Donor Operations Quality Assurance will work closely with operational teams to support the collection of donor derived products. You will be involved in the quality support of collection facility personnel as well as engaged in the review of batch records to ensure the appropriate release of donor material to serve at risk populations.

 

How do you know if you’re the right fit?

This is an exciting opportunity for anyone who excels at active, and creative problem solving. While this is a GMP environment, it is not your typical experience, our program requiring a unique opportunity to apply GMP principles to an area as yet unregulated by the FDA. Our unique product provides the opportunity to grow within a cutting edge GMP program, setting the benchmark for a new industry.

This role requires not only a strong application of GMP principles, but curiosity and attention to details in a fast-paced environment. You will have the opportunity to be a key contributor to the program as well as grow with the organization as it brings a pioneering product to the market. Due to the unique nature of our product, this is not a cookie cutter assembly of requirements, and requires an excitement and attention to detail to understand the unique biology of our product, and the controls necessary to support it. If you’re excited about the opportunity to learn and apply quality controls to a new product, and to grow with our organization, this may be the right place for you.

 

The other stuff

This role is best suited to individuals with at least five years of quality experience, and a Science or Engineering degree. Experience in batch records or auditing is required, as well as in investigation and corrective action assessment for deviations and CAPAs. Strong verbal and written communication is essential, as well as strong interpersonal skills as we work across department lines to ensure we can support donation activities, and the needs of Seres Therapeutics overall.

Apply for the Senior Associate, Quality Assurance (Donor Operations) position

Senior Manager, Donation Collection Facility (DCF)

Seres Therapeutics is well-positioned to become the first company to bring an approved microbiome drug to patients through our proprietary discovery and design platform.  We identify key alterations in the microbiome that are associated with specific diseases and are designing live bacterial ecologies to act as therapeutics.

The Senior Manager, Donation Collection Facility will work closely with the manufacturing, scientific and quality assurance teams to drive biologic material procurement in support of C. difficile patients.  This is a business-critical position; the impact you have on Seres as a key contributor is tremendous.  This is a fantastic opportunity for a very experienced professional with strong experiences in operational management and oversight of a novel biologics procurement program.    

What’s in it for you?

You’ll learn all about our microbiome research and gain an understanding of the biology of specific microbes and the composition of the microbiome in healthy and diseased individuals that allows us to identify “keystone” organisms and functional pathways whose absence or over-abundance may be driving a particular form of dysbiosis.  Learn that our Ecobiotic® drugs are compositions of commensal microbes that are designed to catalyze the transition to a healthy ecology of the microbiome and treat serious human conditions including inflammatory, metabolic, and infectious diseases.  In a nutshell, come to Seres and put your many years of experiences to great use while learning something different that is beyond exciting.

How do you know if you’re the right fit?

This is an incredible opportunity for someone who will get excited about leading the charge on a unique program in support of a pioneering new therapeutic.  You are someone who challenges himself/herself on meeting operational milestones with seamless execution and within established budgets and quality assurance parameters.  You know what it takes to be successful managing operational sites and teams and have demonstrated full competence in continual process improvement and documentation development.

If you have worked in an organization where you managed the procurement of donor derived products, plasma, or blood products, or have experience in facility design and management, you would find this novel leadership opportunity incredibly engaging.

Apply for the Senior Manager, Donation Collection Facility (DCF) position

Senior Manager, Donor Operations – Recruitment Management

What’s in it for you?

Seres Therapeutics is well-positioned to become the first company to bring an approved microbiome drug to patients through our proprietary discovery and design platform.  We identify key alterations in the microbiome that are associated with specific diseases and are designing live bacterial ecologies to act as therapeutics.

The Donor Operations, Recruitment Manager will work closely with our operational teams and facilities to recruit healthy volunteers in support of our donor derived products.  This is a highly visible and business critical position; the impact you have on Seres as a key contributor is tremendous.  This is a fantastic opportunity for a very experienced professional with strong experience in strategic management and execution of a sophisticated, custom-built advertising campaign for volunteer recruitment and screening.    

 

What’s in it for you?

This opportunity is ideal for anyone who excels at creative problem solving and who will drive towards challenging recruitment targets.  Our approach to making drugs is rigorous and refined, and so is our search for donor-volunteers.  This is not your everyday recruitment campaign or effort; our volunteers are unique and our strategic approach to finding them reflects that.  If you are driven, creative and a cross functional team player, you need to consider this position.  It’s truly a one-in-a-million opportunity.

You’ll learn all about our microbiome research and gain an understanding of the biology of specific microbes and the composition of the microbiome in healthy and diseased individuals that allows us to identify “keystone” organisms and functional pathways whose absence or over-abundance may be driving a particular form of dysbiosis. Learn that our Ecobiotic® drugs are compositions of commensal microbes that are designed to catalyze the transition to a healthy ecology of the microbiome and treat serious human conditions including inflammatory, metabolic, and infectious diseases. In a nutshell, come to Seres and put your many years of experiences to great use while learning something different that is beyond exciting.

 

How do you know if you’re the right fit?

This is an incredible opportunity for someone who will get excited about leading the charge on a unique program in support of a pioneering new therapeutic. You are someone who challenges himself/herself on meeting recruitment milestones with seamless execution and within established budgets. You know what it takes to be successful in managing a high-volume program with attention to detail at a rapid pace.

If you are flexible and driven, have worked in a fast-paced organization, and have managed a strategic volunteer recruitment campaign and telephone screening program, you would find this novel opportunity incredibly engaging. 

Apply for the Senior Manager, Donor Operations - Recruitment Management position

The Finance Senior Manager will play a critical role in linking business activities with financial reporting. This individual will be the Finance Business Partner to leaders in Research & Development and G&A functions, creating financial plans and ensuring discipline and transparency in spend through insightful analysis and reporting.

Reporting to the Head of FP&A, this dynamic role spans planning, decision support, accounting and reporting. The successful individual will have a deep understanding of US GAAP, financial processes and advanced analytical capabilities that enable them to support their business partners and Finance leadership.

Key Responsibilities

  • Lead the annual budgeting, forecasting, and long-range planning processes for assigned business functions, partnering with business stakeholders and the Head of FP&A to meet process deadlines and established targets
  • Work with internal stakeholders to create robust functional financial plans. Provide variance reporting for budget and reforecast management
  • Ensure appropriate planning and accounting for R&D and G&A expenses. Work closely with R&D, G&A and Program leads to gain insights into cost drivers
  • Create and maintain robust financial tracking and reporting that empowers business leaders to manage actively functional spend
  • Propose quarter-end accruals, review prepaid amortization schedules and propose adjusting journal entries as needed to ensure proper timing of recognition, statement of related Balance Sheet items and support for review and compliance with SOX controls
  • Analyze relevant inputs, including open purchase orders, invoices, vendor agreements, business feedback and forecasts to determine appropriate recognition of functional expenses in accordance with US GAAP and company policy
  • Partner with department budget owners to provide value-added financial analysis and support of business reviews and decisions from the financial perspective, including but not limited to, operational efficiency, cost saving opportunities, capital expenditure decisions, vendor selection and negotiation, etc.
  • Drive continuous improvement within the finance organization to streamline processes and improve communication and flow of information to the business
  • Other responsibilities as assigned

Qualifications

  • Knowledge and understanding of U.S. GAAP, and SOX compliance requirements
  • Commitment to business partnering with a strong sense of ownership for projects and results
  • Excellent interpersonal skills with a demonstrated ability to work effectively with multiple functional areas in a collaborative, team environment
  • Outstanding communication skills (both written and oral) to influence decision-making
  • Highly proficient in Excel, demonstrated expertise in creating and maintaining forecasts and complex financial models
  • Experience with Oracle Fusion (cloud-based ERP)
  • Possess broad knowledge of accounting concepts and US GAAP, superior analytical skills and knowledge of the biotech industry in order to identify and raise issues and develop policies and procedures

Education

  • Bachelor's degree in Accounting or Finance required, CPA or MBA preferred
  • Minimum of 8 years of finance experience, preferably a combination of public accounting and private industry, with biotech, pharma or medical device preferred ???????
Apply for the Senior Manager, Finance FP&A position

Seres Therapeutics is a dynamic biotechnology company in Cambridge MA pioneering innovative Ecobiotic® microbiome therapeutics. Seres has promising late clinical stage programs and is well-positioned to become the first company to commercialize a new therapeutic modality comprising ecologies of commensal bacteria. Seres plans to enter the clinic with multiple new product candidates in a range of therapeutic areas including infectious disease, inflammation and metabolic disease and to build upon its field-leading portfolio of intellectual property and know-how.


Job Summary
Seres Therapeutics is seeking a highly motivated Senior MSAT (Manufacturing, Science, and Technology)  Engineer to join our Manufacturing Sciences & Technology team. We are focused on developing and supporting manufacturing processes to enable cGMP manufacturing of Seres Therapeutics’ pipeline products. In the role you will work closely with various groups, including Bioprocess Development, Manufacturing Operations, Facilities & Engineering, Supply Chain, Regulatory, Quality Control, and Quality Assurance.


Job Responsibilities

  • Responsible for new product scale-up, process optimization, technology transfer and process validation activities.
  • Serve as technical expert for the drug substance and drug product manufacturing processes on internal and external teams.
  • Manage timelines, deliverables, and personnel from project ideation through completion.
  • Lead and facilitate criticality and risk assessments for manufacturing processes and raw materials, soliciting and incorporating feedback from the appropriate SMEs.
  • Author and execute experiments for process development, characterization, & scale up following the principles of Quality by Design (QbD).
  • Provide technical support for GMP manufacturing runs, supporting manufacturing through quality systems; deviations, CAPAs, & change controls.
  • Perform process performance analysis and trend process performance.

Required Skills and Qualifications

  • BS or MS degree in Biomedical Engineering, Chemical Engineering, Mechanical Engineering or related technical discipline.
  • BS with 8+ years of experience or MS with 6+ years of experience in manufacturing sciences, process development, process validation, or related field.
  • Prior experience with tech transfer, risk assessments, and quality systems in GMP environment.
  • Prior experience with some or all of the following: single-use systems, tangential flow filtration, fermentation, lyophilization.
  • Familiar with FDA and EU regulations and GMP standards.
  • To be successful, you will possess sound understanding of engineering fundamentals, be independently motivated, able to work under aggressive timelines to achieve meaningful objectives, comfortable in a dynamic environment, detail oriented, and possess creative problem-solving abilities.
  • We are looking for a person who meshes well with our culture – eager to dig into whatever work is needed, with a quick learning curve, and do so with high quality results. Collaboration and communication with laboratory and manufacturing colleagues is key!
Apply for the Senior MSAT Engineer position

Vice President, Head of Market Access

 

The Head of Market Access is responsible for leading the strategy, planning, operations, and execution in support of optimal value, profitable access, and pricing/contracting strategy for the entire portfolio of products from Seres Therapeutics, the leading microbiome company.

 

One of the first commercial hires for the company, this individual’s focus will be on preparing for the successful US launch of our SER-109 oral capsule in recurrent C. difficile infection while ensuring pipeline strategies and development plans are optimized to support value.  Initial focus for SER-109 will be for a US launch but this role would support any potential entry to Canada.  We have a strategic collaboration with Nestle Health Sciences for the development and commercialization of both SER-109 and SER-287 outside of the US and Canada.  

 

Reporting directly to the Chief Commercial and Strategy Officer, this key leader will have the opportunity to design and build a world class organization to support optimal patient access for all Seres products.  Remit includes but may not be limited to:  providing leadership and direction of all market access and product distribution strategies; ensuring effective business/contract analytics and systems; delivering strategic insights for launch planning activities; partner with broader Commercial team and program teams in assessment and selection of new products and expansion indications; typical HEOR activities such as value proposition development and evidence generation in support of the value proposition.  As a member of the commercial leadership team, this position will work across the organization to ensure payer perspective and optimized patient access is reflected in key deliverables and decisions supporting commercial launch plans and clinical development.  

 

Seres Therapeutics, Inc., (Nasdaq: MCRB) is a leading microbiome therapeutics platform company developing a novel class of multifunctional bacterial consortia that are designed to functionally interact with host cells and tissues to treat disease. Seres’ SER-109 program achieved the first-ever positive pivotal clinical results for a targeted microbiome drug candidate and has obtained Breakthrough Therapy and Orphan Drug designations from the FDA. The SER-109 program is being advanced for the treatment of recurrent C. difficile infection and has potential to become a first-in-class FDA-approved microbiome therapeutic. Seres’ SER-287 program has obtained Fast Track and Orphan Drug designations from the FDA and is being evaluated in a Phase 2b study in patients with active mild-to-moderate ulcerative colitis. Seres is developing SER-401 in a Phase 1b study in patients with metastatic melanoma, SER-301 for ulcerative colitis and SER-155 to prevent mortality due to gastrointestinal infections, bacteremia and graft versus host disease.

Seres Therapeutics is a member of the Flagship Pioneering family of companies, affording this individual broad exposure and access to other industry leaders in the Flagship fold. 

 

Seres is based in Cambridge, MA.  We recognize the complexities introduced by COVID-19 on travel, necessity for office-based work, and increased value of remote working.  This position will require a mix of Seres corporate office and external stakeholder interfaces therefore we are affording the right candidate flexibility with respect to their East Coast location.  Post-COVID travel will be required to support these critical interfaces. 
 

Responsibilities:

  • Develop and build the market access capability for Seres in support of the upcoming SER-109 launch as well as to optimize further development of a robust pipeline
  • Oversee the development of the overall Market Access strategy, pricing, contracting, and reimbursement and execution in conjunction with other commercial functions (i.e., marketing, sales)
  • Provide input into Company development programs, informing of pricing and market access potential across disease states (across all stages of lifecycle development)
  • Oversees relationships with insurance/managed care organizations and integrated delivery networks, leading key contracting and price negotiations;
  • Develops managed market pricing/contracting strategies consistent with customer and market indications and the overall portfolio targeting long-term commercial success
  • Point of liaison for current and potential future external partners (e.g. with ex-North American partner Nestle Health Sciences) to integrate value proposition work, clinical development plan considerations to support value, and pricing strategies where appropriate for partnered assets
  • Attract, develop, and retain staff members; Inspire and elevate capabilities of others
  • Provide prompt and objective feedback, coaching, and counseling to enhance or improve performance by setting expectations and holding individuals accountable for performance and behavior
  • Leads the strategic and tactical development of distribution for SER-109 as well as contracting, implementation, and operational management of identified 3PL, specialty pharmacies, traditional wholesalers, and specialty distributors
  • Responsible for ensuring necessary chargeback, rebate, and government pricing infrastructure available to execute all private/public pricing and contracting strategies
  • Ensures execution of robust plan to address identified gaps through HEOR studies, publication and message development and influencing, as appropriate; Commission and prepare health economic & outcomes research necessary for reimbursement submissions and competitive messaging
  • Develops and manages departmental budgets that effectively achieve desired goals that are balanced with the financial objectives of the broader commercial organization
  • Ensures compliance with corporate policies and procedures, as well as US healthcare laws and regulations

 

Qualifications:

  • Minimum of a bachelor’s degree; MBA, PharmD, or advanced degree preferred
  • 15+ years of progressive experience within commercial and managed markets roles in account management, formulary access, reimbursement, distribution, program development, contract negotiations and policy development
  • >3 years national or regional direct account management experience with responsibility across multiple US payer types
  • Proven long-term relationships with 3rd party payers (PBMs, commercial / government payers), distribution and trade (3PL, wholesale, specialty pharmacy), physician networks, and healthcare systems
  • Ability to positively position a new company in the Managed Care sector in order to achieve top pharma image and benefits
  • Previous experience successfully developing and leading managed markets/payer initiatives that supported product launches; well versed in pharma/payer contracting terms across various segments; experience with oral drugs, including Medicare Part D
  • Demonstrated leadership ability and track record of career progression; building high-performing commercial teams; strong talent assessment capability and the ability to attract, retain and effectively coach top industry talent to superior performance. Strong ability to effectively engage and motivate people and lead change
  • Superb strategist / visionary who can originate competitive and creative strategies.  Independent thinker with analytical savvy. Ability to quickly manipulate numbers, draw conclusions and exhibit solid problem solving. High level of financial business acumen
  • Prior experience with strategic alliances (establishing and managing strategic relationships such as joint ventures, co-marketing agreements and development partnerships) a plus
  • This hire will be in a role of significant visibility within and outside the company and will possess superb communications skills, the comportment of a professional and the skill of a diplomat. Strong customer orientation
  • Resourceful with strong networking skills.  Flexible, adaptable, diplomatic, and able to effectively deal with ambiguity
  • Possesses a good blend of strategic and operational experience with the ability to see the big picture and strong attention to detail
  • Successful experience in a fast-paced entrepreneurial environment
  • Fit with Seres culture and values, especially encouraging candidates with diverse backgrounds and those who are inclined to listen as much as they are to decide/lead.  Seres is a highly collaborative environment and, therefore, consensus building will be a critical skill to ensure success in this role


 

Apply for the Vice President, Head of Market Access position

Our latest
news

08/10/2020

Seres Announces Positive Topline Results for SER-109
SER-109 met primary endpoint in Phase 3 study in C. difficile

READ MORE